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Title: Nano-structured lipid carriers: A promising strategy and current progress in rheumatoid arthritis and pain management
Authors: Sharma N
Sharma S
Singh S
Garg K
Singh S.K
Arora S.
Keywords: Homogenization technique
Nano-structured lipid carriers
Pain management
Rheumatoid arthritis
Issue Date: 2020
Publisher: Plant Archives
Abstract: Rheumatoid arthritis is among the predominant holistic and persistent joint-related autoimmune diseases that causes in physical impairment and impaired quality of functioning, since bone & cartilage degradation, joint inflammation, as well as pain arise. Despite significant innovations in treatment strategies, restrictions on treatment routes and A requirement for a regular, long-term dosage have manifested in clinical unpleasant effects and patient rebellion that could have been controlled through producing nano-structured lipid carriers (NLCs) based systems. Pain is another prevalent and growing global medical challenge which has enormous economic and social impact to both patients and medical-care services, and therefore on the society overall. NLCs offer a fascinating opportunity as innovative strategies to pick up safety and effectiveness of the medications widely used for pain relief. In this article, we reviewed the benefits and drawbacks, classification, components used and manufacturing techniques, i.e. the methodology of heat and cold homogenization for NLCs. A summary was also elucidated of the types and pathogenesis of rheumatoid arthritis. Here we explore a wide range of NLC formulations produced to encapsulate a variety of medication to treat rheumatoid arthritis as well as pain illnesses, their compositions and methodologies of preparation. � 2020 Plant Archives. All rights reserved.
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