Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1572
Title: Thiolation of biopolymers for developing drug delivery systems with enhanced mechanical and mucoadhesive properties: A review
Authors: Puri V.
Sharma A
Kumar P
Singh I.
Keywords: Thiolation
biopolymers
drug delivery systems
mechanical properties
mucoadhesive properties
patents
Issue Date: 2020
Publisher: MDPI AG
Abstract: Biopolymers are extensively used for developing drug delivery systems as they are easily available, economical, readily modified, nontoxic, biodegradable and biocompatible. Thiolation is a well reported approach for enhancing mucoadhesive and mechanical properties of polymers. In the present review article, for the modification of biopolymers different thiolation methods and evaluation/characterization techniques have been discussed in detail. Reported literature on thiolated biopolymers with enhanced mechanical and mucoadhesive properties has been presented conspicuously in text as well as in tabular form. Patents filed by researchers on thiolated polymers have also been presented. In conclusion, thiolation is an easily reproducible and efficient method for customization of mucoadhesive and mechanical properties of biopolymers for drug delivery applications.
URI: 10.3390/polym12081803
http://hdl.handle.net/123456789/1572
Appears in Collections:Journals

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