Please use this identifier to cite or link to this item: http://hdl.handle.net/1/870
Title: Radiolysis of Nucleosides: Study of Sedimentary Microenvironment Models for the Protection of Bio-Organic Molecules on Early Earth
Authors: OVANDO, E Y AGUILAR
MENDOZA, A NEGRÓN
Keywords: Chemical Evolution
Clays
Nucleosides
Ionizing Radiation
Issue Date: 7-Aug-2017
Publisher: Chitkara University Publications
Abstract: Nucleic acid bases and their derivatives are important compounds in biological systems. Many efforts have been made to demonstrate the possible prebiotic origin of these molecules, but the abiotic synthesis of these compounds has proved to be very difficult in that conditions. So, if their synthesis actually took place, a study of their stability in prebiotic conditions is quite relevant in chemical evolution studies. In this work, it has been examined and compared the influence of Sodium Montmorillonite on the chemical transformations undergone by two nucleosides (guanosine – purinic– and uridine, –pyrimidinic–) when subjected to conditions simulating the primitive Earth during the period of chemical evolution. The experiments prove the concentration capacity and protective role against external sources of ionizing radiation (specifically γ-ray) that clays can provide to these specific compounds adsorbed on them. By using X-ray diffraction, UVvis spectrophotometry and HPLC for the analysis, it was found that purinic nucleosides (more than pyrimidinic) are quickly adsorbed on clay at low pH values, and the temperature of mineral desiccation applied after adsorption promotes their decomposition into their corresponding nitrogenous bases. In both, purinic and pyrimidinic, desorption occurs in neutral or slightly basic aqueous solutions, and both are protected by clay. Pyrimidinic nucleosides show more resistance to heat, but less resistance towards ionizing radiation, even when adsorbed in clay.
URI: http://dspace.chitkara.edu.in/xmlui/handle/1/870
http://hdl.handle.net/1/870
ISSN: Print 2321-8649
Online 2321-9289
Appears in Collections:JNP Volume 5 Number 1 (August - 2017)

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