Browsing by Author "Gurpreet Kaur"

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    A Quasi Experimental Study to Compare the Effect of Semi-Sitting Versus Left Lateral Position on Maternal and Foetal Bio-Physiological Parameters Among Antenatal Women Undergoing Non Stress Test in Tertiary Care Hospital of Patiala, Punjab
    (Chitkara University Publications, 2017-10-02) Gurpreet Kaur; Preety Narula; Harpreet Kaur
    Background of the study NST is a simple, non invasive test performed in pregnancy over 28 weeks of gestation. Pregnant women are generally positioned in the supine position because this position allow easy administration of the test. But supine position cause aortacaval compression which decrease blood supply to the fetus hence shows non reactive results. Hence position is one of the main factor which should be considered during non stress test. Methodology Aquasi experimental design was used. Total 60 antenatal women (30 experimental group I, 30 experimental group II) was selected by purposive sampling technique. Data collection method- Baseline maternal foetal bio-physiological parameters were assessed by performing NST for 10 minutes in baseline position(supine position) among experimental groups and then after a gap of 10 minutes semi-sitting and left lateral position was given to experimental group I and II respectively. Maternal and foetal bio-physiological parameters were assessed after 10 minutes of NST in both experimental groups I and II. Results Result of the present study revealed that baseline (supine) when compared with Semi-sitting position had significant effect on maternal foetal bio-physiological parameters at (p<0.05) level of significance however when baseline (supine) compared with left lateral position had no significant effect on maternal bio- physiological parameters except on pulse rate at (p<0.05) level of significance whereas left lateral position had significant effect on foetal bio-physiological parameters except baseline heart rate and deceleration at (p<0.05) level of significance. When semi-sitting compared with left lateral had no significant effect on maternal foetal bio-physiological parameters at (p<0.05) level of significance. Conclusion Baseline position(supine) when altered to semi-sitting or left lateral position influence the maternal foetal bio-physiological parameters. Semi-sitting when compared with left lateral had no significant effect on maternal and foetal bio- physiological parameters.
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    Comprehensive Insights into Lipid Nanocarriers: Preparation, Characterization and Applications
    (Chitkara University Publications, 2026-08-04) Ravi Goyal; Gurpreet Kaur; Sumit Sharma; Deepika Raina; Nitin Chitranshi
    Background: Lipid nanocarriers have emerged as a novel alternative to traditional drug delivery systems such as emulsions, liposomes, and microparticulate systems. These are spherical nano-sized (1–1000 nm) colloidal carriers dispersed in an aqueous surfactant solution. Their biodegradable, biocompatible, and non-toxic nature has led to extensive exploration in clinical medicine for multiple routes of administration, including oral, parenteral, and topical delivery. They offer high stability, large drug-loading capacity, and the ability to deliver both hydrophilic and lipophilic drugs in a targeted and controlled manner. Purpose: The purpose of this review is to provide a comprehensive overview of lipid nanocarriers, focusing on their fundamental principles, advantages, limitations, preparation methods, and characterization techniques. Methods: The review compiles and analyzes literature from relevant publications from the last 15 years on lipid nanocarriers, covering their formulation approaches, different preparation techniques, and evaluation parameters used to assess their physicochemical and functional properties. Results: Lipid nanocarriers demonstrate significant advantages, including enhanced stability, improved drug loading, controlled and targeted drug release, and adaptability to various formulation requirements. Their versatility makes them suitable for applications in pharmaceuticals, vaccines, nutraceuticals, and diagnostic systems. Conclusions: A comprehensive understanding of lipid nanocarriers can open new avenues in the treatment of multifactorial disorders. Their safety, efficacy, and flexibility position them as promising candidates for advanced drug delivery systems and future therapeutic innovations.