Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/670
Title: Ebola Hemorrhagic Fever: Recent Update On Disease Status, Current Therapies And Advances In Treatment
Authors: SINGH, JASKARAN
KOMA, THAPA
ARORA, SANDEEP
KAUR, AMARJOT
SINGH, THAKUR GURJEET
Keywords: Filovirus
Ebola
Single-stranded ribonucleic acid
GRADE
vaccines
rVSV-EBOV
Favipiravir
ZMapp
Issue Date: 2-Nov-2017
Publisher: Chitkara University Publications
Abstract: Swiftly growing viruses are a major intimidation to human health. Such viruses are extremely pathogenic like Ebola virus, influenza virus, HIV virus, Zika virus etc . Ebola virus, a type of Filovirus, is an extremely infectious, single-stranded ribonucleic acid virus that infects both humans and apes, prompting acute fever with hemorrhagic syndrome. The high infectivity, severity and mortality of Ebola has plagued the world for the past fifty years with its first outbreak in 1976 in Marburg, Germany, and Frankfurt along with Belgrade and Serbia. The world has perceived about 28,000 cases and over 11,000 losses. The high lethality of Ebola makes it a candidate for use in bioterrorism thereby arising more concern. New guidelines have been framed for providing best possible care to the patients suffering from Ebola virus i.e Grading of Recommendation Assessment, Development And Evaluation (GRADE) methodology to develop evidence-based strategy for the treatment in future outbreak of Ebola virus. No drugs have been approved, while many potent drugs like rVSV-EBOV, Favipiravir, ZMapp are on clinical test for human safety. In this review we will discover and discuss perspective aspects that lead to the evolution of different Ebola variants as well as advances in various drugs and vaccines for treatment of the disease.
URI: http://hdl.handle.net/123456789/670
ISSN: Print 2321-2217
Online 2321-2225
Appears in Collections:JPTRM Volume 5 Number 2 (November - 2017)

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